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Diagnosis is made by isolating E coli on blood agar and then having the isolate biotyped or serotyped. Electron micrographs of E coli attached to the mucosa are also helpful. In extreme cases, remedy just isn’t profitable; in mild cases, antibiotics could also be effective.
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Procaine penicillin (60,000 IU/kg/day, SC, for 7 days) can be beneficial for individual rabbits. All rabbits must be treated even if no lesions are present. Lesions normally heal inside 10–14 days, and recovered rabbits could be bred without danger of transmitting the an infection. Death happens in 5–14 days, or rabbits are left stunted and unthrifty.
Severely affected rabbits should be culled, and facilities thoroughly sanitized. High-fiber diets seem to help prevent the illness in weaned rabbits. Additional therapies could embody anti-inflammatory medicine, cautious flushing of the nasolacrimal duct, nebulization therapy, ear and eye drops, administration of fluids, and surgical procedure. Systemic NSAIDs similar to meloxicam must also be used. Treatment can embrace gentle saline flushing of the duct through the nasolacrimal punctum, however care is warranted to not injury the nasolacrimal duct throughout flushing. Any mechanical harm to the delicate tear duct can result in everlasting epiphora, and homeowners must be suggested accordingly.
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Conjunctivitis and dacryocystitis is a standard downside in rabbits. Predisposing elements embody mechanical irritation, eyelid ailments, and dental disease. Conjunctivitis in rabbits could also be related to different disease processes, particularly dacryocystitis. The most incriminated cause of conjunctivitis is P multocida; however, this may be solely a secondary infection.